Article
Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression.
Molecular microbiology - 1 Feb 2004
Beloin Christophe, Valle Jaione, Latour-Lambert Patricia, Faure Philippe, Kzreminski Mickaël, Balestrino Damien, Haagensen Janus A J, Molin Søren, Prensier Gérard, Arbeille Brigitte, Ghigo Jean-Marc
Abstract excerpt
The formation of biofilm results in a major lifestyle switch that is thought to affect the expression of multiple genes and operons. We used DNA arrays to study the global effect of biofilm formation on gene expression in mature Escherichia coli K-12 biofilm. We show that, when biofilm is compared with the exponential growth phase, 1.9% of the genes showed a consistent up- or downregulation by a factor greater...
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