Article
Establishment and characterization of human engineered cells stably expressing large extracellular matrix proteins.
Archives of pharmacal research - 1 Jan 2014
Kwon Daekee, Kang Gwang-Sik, Han Dong Keun, Park Kwideok, Kim Jae-Hwan, Lee Soo-Hong
Abstract excerpt
Commercially available extracellular matrix (ECM) hydrogel-coated culture plates have been used to study the relationship between the ECM microenvironment and stem cell behavior. However, it is unclear whether ECM-coated dishes mimic the natural ECM microenvironment because the architecture of the ECM is constructed of randomly distributed fibers. The purpose of this study was the production and confirmation of...
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