Article
The usefulness of genotyping cytochrome P450 enzymes in the treatment of depression.
Expert opinion on drug metabolism & toxicology - 1 Mar 2015
Dubovsky Steven L
Abstract excerpt
INTRODUCTION: Pharmacogenomics, which is derived from genome-wide association studies (GWAS), and pharmacogenetics, which involves candidate gene association studies (CGASs), are proving increasingly useful in personalized cancer care. Research in psychiatric applications has primarily involved genetic polymorphisms of P450 CYP enzymes, which mediate oxidative metabolism, particularly CYP2D6, which is involved in...
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