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Article

Sun exposure, vitamin D receptor genetic variants, and risk of breast cancer in the Agricultural Health Study.

Environmental health perspectives - 1 Feb 2014

Engel Lawrence S, Satagopan Jaya, Sima Camelia S, Orlow Irene, Mujumdar Urvi, Coble Joseph, Roy Pampa, Yoo Sarah, Sandler Dale P, Alavanja Michael C

Abstract excerpt

BACKGROUND: Epidemiologic evidence suggests a negative relation between sunlight exposure and breast cancer risk. The hypothesized mechanism is sunlight-induced cutaneous synthesis of vitamin D. OBJECTIVES: Our goal was to examine sun exposure and its interaction with vitamin D receptor (VDR) gene variants on breast cancer risk. METHODS: We examined sun exposure and breast cancer incidence among 31,021 private...

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Identifiers

PMID: 24252436
DOI: 10.1289/ehp.1206274
PMCID: PMC3915256

Genes

VDR

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