Article
Early life sun exposure, vitamin D-related gene variants, and risk of non-Hodgkin lymphoma.
Cancer causes & control : CCC - 1 Jul 2012
Kelly Jennifer L, Drake Matthew T, Fredericksen Zachary S, Asmann Yan W, Liebow Mark, Shanafelt Tait D, Feldman Andrew L, Ansell Stephen M, Macon William R, Herr Megan M, Wang Alice H, Nowakowski Grzegorz S, Call Timothy G, Habermann Thomas M, Slager Susan L, Witzig Thomas E, Cerhan James R
Abstract excerpt
PURPOSE: It has been hypothesized that vitamin D mediates the inverse relationship between sun exposure and non-Hodgkin lymphoma (NHL) risk reported in several recent studies. We evaluated the association of self-reported sun exposure at ages <13, 13-21, 22-40, and 41+ years and 19 single nucleotide polymorphisms (SNPs) from 4 candidate genes relevant to vitamin D metabolism (RXR, VDR , CYP24A1, CYP27B1) with NHL...
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