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Sunlight, polymorphisms of vitamin D-related genes and risk of breast cancer.

Anticancer research - 1 Feb 2013

Fuhrman Barbara J, Freedman D Michal, Bhatti Parveen, Doody Michele M, Fu Yi-Ping, Chang Shih-Chen, Linet Martha S, Sigurdson Alice J

Abstract excerpt

BACKGROUND/AIM: Geographic gradients in breast cancer incidence and mortality suggest that vitamin D may reduce risk. The enzyme 25-hydroxyvitamin D 24-hydroxylase (CYP24A1), which degrades the active form of vitamin D, and the vitamin D receptor (VDR) are both found in breast tissue. We investigated six polymorphisms in CYP24A1 and two in the VDR gene in association with breast cancer risk. MATERIALS AND...

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Source

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Identifiers

PMID: 23393347
PMCID: PMC3866631

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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