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Article

Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis.

Acta neuropathologica communications - 30 Jul 2013

Freischmidt Axel, Müller Kathrin, Ludolph Albert C, Weishaupt Jochen H

Abstract excerpt

BACKGROUND: A pathological hallmark of most amyotrophic lateral sclerosis (ALS) cases are intracellular aggregates of the protein TDP-43. The pathophysiological relevance of TDP-43 is underlined by familial ALS cases caused by TDP-43 mutations. TDP-43 is involved in processing of both coding RNAs...

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Share to Amyotrophic Lateral Sclerosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24252274
DOI: 10.1186/2051-5960-1-42
PMCID: PMC3893596

Genes

SOD1
FUS
TARDBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24252274-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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