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Article

Identification of plasma microRNAs as a biomarker of sporadic Amyotrophic Lateral Sclerosis

24 Oct 2015

Abstract excerpt

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease, which leads to the loss of upper and lower motor neurons, with a currently unknown etiology. Specific biomarkers could help in early detection and diagnosis, and could also act as indicators of disease progression and therapy effectiveness. MicroRNAs (miRNAs) are small (18-25 nucleotides), single-stranded non-coding RNA...

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PMID: 26497046
DOI: 10.1186/s13041-015-0161-7

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