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Article

Systems biology of primary CNS lymphoma: from genetic aberrations to modeling in mice.

Acta neuropathologica - 1 Feb 2014

Deckert Martina, Montesinos-Rongen Manuel, Brunn Anna, Siebert Reiner

Abstract excerpt

Primary lymphoma of the central nervous system (CNS, PCNSL) is a specific diffuse large B cell lymphoma entity arising in and confined to the CNS. Despite extensive research since many decades, the pathogenetic mechanisms underlying the remarkable tropism of this peculiar malignant hematopoietic tumor remain still to be elucidated. In the present review, we summarize the present knowledge on the genotypic and...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, Large B-Cell, Diffuse

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Source

Identifiers

PMID: 24240734
DOI: 10.1007/s00401-013-1202-x

Genes

BCL2
MYC
BCL6
BCR
BLNK
CARD11
CBL
MALT1
MYD88
PAX5
PIM1
PRDM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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