Article
The brachyury Gly177Asp SNP is not associated with a risk of skull base chordoma in the Chinese population.
International journal of molecular sciences - 25 Oct 2013
Wu Zhen, Wang Ke, Wang Liang, Feng Jie, Hao Shuyu, Tian Kaibing, Zhang Liwei, Jia Guijun, Wan Hong, Zhang Junting
Abstract excerpt
A recent chordoma cancer genotyping study reveals that the rs2305089, a single nucleotide polymorphism (SNP) located in brachyury gene and a key gene in the development of notochord, is significantly associated with chordoma risk. The brachyury gene is believed to be one of the key genes involved in the pathogenesis of chordoma, a rare primary bone tumor originating along the spinal column or at the base of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.