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Article

Genetic aberrations and molecular biology of skull base chordoma and chondrosarcoma.

Brain tumor pathology - 1 Apr 2017

Kitamura Yohei, Sasaki Hikaru, Yoshida Kazunari

Abstract excerpt

Chordomas and chondrosarcomas are two major malignant bone neoplasms located at the skull base. These tumors are rarely metastatic, but can be locally invasive and resistant to conventional chemotherapies and radiotherapies. Accordingly, therapeutic approaches for the treatment of these tumors can be difficult. Additionally, their location at the skull base makes them problematic. Although accurate diagnosis of...

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Identifiers

PMID: 28432450
DOI: 10.1007/s10014-017-0283-y

Genes

IDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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