Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular and Clinical Risk Factors for Recurrence of Skull Base Chordomas

21 Aug 2013

Abstract excerpt

Chordomas are invasive tumors that develop from notochordal remnants and frequently occur in the skull base. The T gene and its product (brachyury) have recently been suggested to play an important role in chordoma progression. To date, few studies have investigated the relationship between the molecular/genetic characteristics of chordoma and patient prognosis. We analyzed 37 skull base chordomas for chromosomal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Tumor Diagnosis and Treatments
Share to Oral and Maxillofacial Pathology
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23965741
DOI: 10.1097/nen.0b013e3182a065d0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular and Clinical Risk Factors for Recurrence of Skull Base ChordomasPMID 23965741Read ↗

Genetic aberrations and molecular biology of skull base chordoma and chondrosarcoma.Semantic proximity Read ↗

Brachyury gene copy number gain and activation of the PI3K/Akt pathway: association with upregulation of oncogenic Brachyury expression in skull base chordomaSemantic proximity Read ↗

Unraveling molecular advancements in chordoma tumorigenesis and treatment response: a review of scientific discoveries and clinical implicationsSemantic proximity Read ↗

Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular targetSemantic proximity Read ↗

Identification of the Different Roles and Potential Mechanisms of T Isoforms in the Tumor Recurrence and Cell Cycle of ChordomasSemantic proximity Read ↗

From Notochord Formation to Hereditary Chordoma: The Many Roles of<i>Brachyury</i>Semantic proximity Read ↗

Chordoma: Genetics and Contemporary Management.Semantic proximity Read ↗

An Integrated Management Paradigm for Skull Base Chordoma Based on Clinical and Molecular CharacteristicsSemantic proximity Read ↗

Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study.Semantic proximity Read ↗

Spinal column chordoma: prognostic significance of clinical variables and T (brachyury) gene SNP rs2305089 for local recurrence and overall survival.Semantic proximity Read ↗

The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target.Semantic proximity Read ↗

Brachyury expression is highly specific for chordoma: A tissue microarray study involving 14,976 cancers from 135 different tumor types and subtypesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.