Article
Direct RNA-based detection and differentiation of CTX-M-type extended-spectrum β-lactamases (ESBL).
PloS one - 1 Jan 2013
Stein Claudia, Makarewicz Oliwia, Pfeifer Yvonne, Brandt Christian, Ramos João Costa, Klinger Mareike, Pletz Mathias W
Abstract excerpt
The current global spread of multi-resistant Gram-negatives, particularly extended spectrum β-lactamases expressing bacteria, increases the likelihood of inappropriate empiric treatment of critically ill patients with subsequently increased mortality. From a clinical perspective, fast detection of resistant pathogens would allow a pre-emptive correction of an initially inappropriate treatment. Here we present...
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