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Article

Roles of the linker region of RNA helicase A in HIV-1 RNA metabolism.

PloS one - 1 Jan 2013

Xing Li, Niu Meijuan, Zhao Xia, Kleiman Lawrence

Abstract excerpt

RNA helicase A (RHA) promotes multiple steps in HIV-1 production including transcription and translation of viral RNA, annealing of primer tRNA(Lys3) to viral RNA, and elevating the ratio of unspliced to spliced viral RNA. At its amino terminus are two double-stranded RNA binding domains (dsRBDs) that are essential for RHA-viral RNA interaction. Linking the dsRBDs to the core helicase domain is a linker region...

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Identifiers

PMID: 24223160
DOI: 10.1371/journal.pone.0078596
PMCID: PMC3819368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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