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Article

Coordinate roles of Gag and RNA helicase A in promoting the annealing of formula to HIV-1 RNA.

Journal of virology - 1 Feb 2011

Xing Li, Liang Chen, Kleiman Lawrence

Abstract excerpt

RNA helicase A (RHA) has been shown to promote HIV-1 replication at both the translation and reverse transcription stages. A prerequisite step for reverse transcription involves the annealing of tRNA(3)(Lys), the primer for reverse transcription, to HIV-1 RNA. tRNA(3)(Lys) annealing is a multistep process that is initially facilitated by Gag prior to viral protein processing. Herein, we report that RHA promotes...

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Share to gag Gene Products, Human Immunodeficiency Virus
Share to Genes, gag
Share to HEK293 Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to RNA, Transfer, Lys

Source

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Identifiers

PMID: 21106734
DOI: 10.1128/JVI.02010-10
PMCID: PMC3028891

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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