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Article

Transcriptome- and proteome-wide association studies identify genes associated with renal cell carcinoma.

American journal of human genetics - 5 Sept 2024

Dutta Diptavo, Guo Xinyu, Winter Timothy D, Jahagirdar Om, Ha Eunji, Susztak Katalin, Machiela Mitchell J, Chanock Stephen J, Purdue Mark P

Abstract excerpt

We performed a series of integrative analyses including transcriptome-wide association studies (TWASs) and proteome-wide association studies (PWASs) of renal cell carcinoma (RCC) to nominate and prioritize molecular targets for laboratory investigation. On the basis of a genome-wide association study (GWAS) of 29,020 affected individuals and 835,670 control individuals and prediction models trained in...

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Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genome-Wide Association Study

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 39137781
DOI: 10.1016/j.ajhg.2024.07.012
PMCID: PMC11393681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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