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Article

A role for IRF8 in B cell anergy.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2013

Pathak Simanta, Ma Shibin, Shukla Vipul, Lu Runqing

Abstract excerpt

B cell central tolerance is a process through which self-reactive B cells are removed from the B cell repertoire. Self-reactive B cells are generally removed by receptor editing in the bone marrow and by anergy induction in the periphery. IRF8 is a critical transcriptional regulator of immune system development and function. A recent study showed that marginal zone B cell and B1 B cell populations are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24218455
DOI: 10.4049/jimmunol.1301169
PMCID: PMC3864091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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