Zebrafish models of acute leukemias: Current models and future directions.

Abstract excerpt

Acute myeloid leukemias (AML) and acute lymphoid leukemias (ALL) are heterogenous diseases encompassing a wide array of genetic mutations with both loss and gain of function phenotypes. Ultimately, these both result in the clonal overgrowth of blast cells in the bone marrow, peripheral blood, and other tissues. As a consequence of this, normal hematopoietic stem cell function is severely hampered. Technologies...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hematopoietic Stem Cells
• Share to Leukemia, Myeloid, Acute