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Article

Exclusive induction of G:C to A:T transitions by 3-azido-1,2-propanediol in yeast.

Mutation research. Genetic toxicology and environmental mutagenesis - 15 Jan 2014

Grúz Petr, Sassa Akira, Hosoda Akemi, Yamagishi Hiroyuki, Usui Yukio, Shimizu Masatomi

Abstract excerpt

Sodium azide is a strong mutagen which has been successfully employed in mutation breeding of crop plants. In biological systems, it is metabolized to azidoalanine, but further bioactivation to a putative ultimate mutagen as well as the nature of the induced DNA modifications leading to mutations remain elusive. In this study, mutations induced in the CAN1 gene of yeast Saccharomyces cerevisiae by the...

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Identifiers

PMID: 24211442
DOI: 10.1016/j.mrgentox.2013.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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