Article
Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus.
Human genetics - 1 May 2013
Patel Chirag J, Chen Rong, Kodama Keiichi, Ioannidis John P A, Butte Atul J
Abstract excerpt
Diseases such as type 2 diabetes (T2D) result from environmental and genetic factors, and risk varies considerably in the population. T2D-related genetic loci discovered to date explain only a small portion of the T2D heritability. Some heritability may be due to gene-environment interactions. However, documenting these interactions has been difficult due to low availability of concurrent genetic and...
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