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Article

Pyrosequencing for EGFR mutation detection: diagnostic accuracy and clinical implications.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 2013

Sahnane Nora, Gueli Rossana, Tibiletti Maria G, Bernasconi Barbara, Stefanoli Michele, Franzi Francesca, Pinotti Graziella, Capella Carlo, Furlan Daniela

Abstract excerpt

EGFR-activating mutations predict responsiveness to EGFR tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) patients. Mutation screening is crucial to support therapeutic decisions and is commonly conducted using dideoxy sequencing, although its sensitivity is suboptimal in c...

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Source

Identifiers

PMID: 24193003
DOI: 10.1097/PDM.0b013e3182893f55

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24193003-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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