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Article

Role of Connexin 43 in Helicobacter pylori VacA-Induced Cell Death

5 Nov 2013

Abstract excerpt

Helicobacter pylori colonizes the human stomach and confers an increased risk for the development of peptic ulceration, noncardia gastric adenocarcinoma, and gastric lymphoma. A secreted H. pylori toxin, VacA, can cause multiple alterations in gastric epithelial cells, including cell death. In this study, we sought to identify host cell factors that are required for VacA-induced cell death. To do this, we...

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PMID: 24191302
DOI: 10.1128/iai.00827-13

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Role of Connexin 43 in Helicobacter pylori VacA-Induced Cell DeathPMID 24191302Read ↗

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