Article
Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis
1 Jan 2012
Abstract excerpt
More than 50% of the world's population is infected with Helicobacter pylori (H. pylori). Chronic infection with this Gram-negative pathogen is associated with the development of peptic ulcers and is linked to an increased risk of gastric cancer. H. pylori secretes many proteinaceous factors that are important for initial colonization and subsequent persistence in the host stomach. One of the major protein toxins...
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