Article
Association of genetic variants of cancer stem cell gene CD44 haplotypes with gallbladder cancer susceptibility in North Indian population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2014
Sharma Kiran Lata, Yadav Anu, Gupta Annapurna, Tulsayan Sonam, Kumar Vijay, Misra Sanjeev, Kumar Ashok, Mittal Balraj
Abstract excerpt
CD44 is an important marker for cancer stem cells. Germline variants in CD44 gene have been associated with susceptibility to breast and nasopharyngeal carcinomas but no study in gallbladder cancer (GBC) has been done yet. The present study included 405 GBC patients and 200 healthy controls from North India. Tagger SNPs for CD44 were selected from the GIH population data. Genotyping was carried out by PCR-RFLP...
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