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Article

Role of SMOC2 in adenomyosis: implications for ECM remodeling and EMT pathogenesis

3 Apr 2025

Abstract excerpt

BACKGROUND: Adenomyosis is a common gynecological disorder characterized by the invasion of endometrial tissue into the myometrium, resulting in severe dysmenorrhea and menorrhagia. This study aimed to explore the role of SMOC2 (SPARC related modular calcium binding 2), an extracellular matrix (ECM) -associated protein, in the pathogenesis of adenomyosis and its potential as a therapeutic target. METHODS: We...

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Share to Endometriosis Research and Treatment
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PMID: 40181364
DOI: 10.1186/s12905-025-03700-8

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