Article
Genetic features of endometrioid-type endometrial carcinoma arising in uterine adenomyosis.
Virchows Archiv : an international journal of pathology - 1 Jul 2022
Yoshida Hiroshi, Asami Yuka, Kobayashi-Kato Mayumi, Tanase Yasuhito, Uno Masaya, Ishikawa Mitsuya, Shiraishi Kouya, Kato Tomoyasu
Abstract excerpt
This study aimed to clarify the genetic features of endometrioid-type endometrial cancer arising in adenomyosis (EC-AIA) using targeted sequencing and immunohistochemistry (IHC) for both carcinoma and adjacent adenomyosis tissues. We identified three endometrioid-type EC-AIAs in 689 patients with endometrial cancer; two exhibited grade 3 endometrioid carcinoma. IHC revealed retained expression of PMS2, MSH6,...
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