Article
PIK3CA and AKT gene polymorphisms in susceptibility to osteosarcoma in a Chinese population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
He Mao-Lin, Wu Yang, Zhao Jin-Min, Wang Zhe, Chen Ying-Bin
Abstract excerpt
PURPOSE: To explore the association between PIK3CA and AKT single nucleotide polymorphisms(SNP) and osteosarcoma susceptibility. METHODS: TaqMan polymerase chain reaction(PCR) was used to detect the genotypes of SNPs (rs7646409, rs6973569 and rs9866361) in peripheral blood samples from 59 patients with osteosarcoma and from 63 healthy controls. Unconditional logistic regression was used to analyze the correlation...
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