Genetic variations in the PRKCG gene and osteosarcoma risk in a Chinese population: a case-control study.

doi:10.1007/s13277-015-3182-z

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genetic variations in the PRKCG gene and osteosarcoma risk in a Chinese population: a case-control study.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2015

Lu Huading, Zhu Lei, Lian Liyi, Chen Mingwei, Shi Dehai, Wang Kun

Abstract excerpt

Osteosarcoma is a common malignant tumor, which exists widely in the bone of children and adolescents. Protein kinase C gamma (PRKCG) gene, which encodes γPKC, plays important roles in tumor promotion, cell proliferation, differentiation, and migration. The objective of the present study was to investigate the relationship between PRKCG polymorphisms and the risk of osteosarcoma. Five tag single nucleotide...

Topics

Adolescent
Asian People
Bone Neoplasms
Case-Control Studies
Child
Child, Preschool
China
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Neoplasm Staging

Osteosarcoma

Polymorphism, Single Nucleotide

Protein Kinase C

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 25663494
DOI: 10.1007/s13277-015-3182-z

Genes

PRKCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations in the PRKCG gene and osteosarcoma risk in a Chinese population: a case-control study.PMID 25663494Read ↗

Single-nucleotide polymorphisms of the PRKCG gene and osteosarcoma susceptibility.Semantic proximity Read ↗

PIK3CA and AKT gene polymorphisms in susceptibility to osteosarcoma in a Chinese population.Semantic proximity Read ↗

Genetic variants associated with osteosarcoma risk: a systematic review and meta-analysis.Semantic proximity Read ↗

Associations of polymorphisms in the bone morphogenetic protein-2 gene with risk and prognosis of osteosarcoma in a Chinese population.Semantic proximity Read ↗

A comprehensive evaluation of single nucleotide polymorphisms associated with osteosarcoma risk: A protocol for systematic review and network meta-analysis.Semantic proximity Read ↗

Impact of common SNPs in VEGF gene on the susceptibility of osteosarcoma.Semantic proximity Read ↗

Association of GRM4 gene polymorphisms with susceptibility and clinicopathological characteristics of osteosarcoma in Guangxi Chinese population.Semantic proximity Read ↗

Association of ITGA3 gene polymorphisms with susceptibility and clinicopathological characteristics of osteosarcoma.Semantic proximity Read ↗

Polymorphisms in TP53 are associated with risk and survival of osteosarcoma in a Chinese population.Semantic proximity Read ↗

Haplotype analysis on relationship of ERCC2 and ERCC3 gene polymorphisms with osteosarcoma risk in Chinese young population.Semantic proximity Read ↗

Role of ERCC2 and ERCC3 gene polymorphisms in the development of osteosarcoma.Semantic proximity Read ↗

GRM4 gene polymorphism is associated with susceptibility and prognosis of osteosarcoma in a Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.