Article
IL23R polymorphisms influence phenotype and response to therapy in patients with ulcerative colitis.
European journal of gastroenterology & hepatology - 1 Jan 2014
Cravo Marília L, Ferreira Paula A, Sousa Patricia, Moura-Santos Paula, Velho Sónia, Tavares Lurdes, de Deus João R, Ministro Paula, Peixe Paula, Correia Luis A, Velosa José F, Maio Rui F, Brito Miguel
Abstract excerpt
OBJECTIVE: We aimed to identify the clinical and genetic [IL23 receptor (IL23R) single nucleotide polymorphisms (SNPs)] predictors of response to therapy in patients with ulcerative colitis. PATIENTS AND METHODS: A total of 174 patients with ulcerative colitis, 99 women and 75 men, were included. The mean age of the patients was 47±15 years and the mean disease duration was 11±9 years. The number of patients...
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