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Article

A prospective, multi-institutional diagnostic trial to determine pathologist accuracy in estimation of percentage of malignant cells.

Archives of pathology & laboratory medicine - 1 Nov 2013

Viray Hollis, Li Kevin, Long Thomas A, Vasalos Patricia, Bridge Julia A, Jennings Lawrence J, Halling Kevin C, Hameed Meera, Rimm David L

Abstract excerpt

CONTEXT: The fraction of malignant cells in tumor tissue submitted for tests of genetic alterations is a critical variable in testing accuracy. That fraction is currently determined by pathologist visual estimation of the percentage of malignant cells. Inaccuracy could lead to a false-negative test result. OBJECTIVE: To describe a prospective, multi-institutional study to determine pathologist estimation...

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PMID: 24168492
DOI: 10.5858/arpa.2012-0561-CP

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KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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