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Article

Association of low baseline levels of erythrocyte folate with treatment nonresponse at three months in rheumatoid arthritis patients receiving methotrexate.

Arthritis and rheumatism - 1 Nov 2013

de Rotte M C F J, de Jong P H P, Pluijm S M F, Calasan M Bulatović, Barendregt P J, van Zeben D, van der Lubbe P A, de Sonnaville P B, Lindemans J, Hazes J M W, de Jonge R

Abstract excerpt

OBJECTIVE: To investigate whether baseline concentrations of one-carbon metabolism biomarkers are associated with treatment nonresponse and adverse events in rheumatoid arthritis (RA) patients receiving methotrexate (MTX). METHODS: A prospective derivation cohort (n = 285) and validation cohort (n = 102) of RA patients receiving MTX were studied. Concentrations of plasma homocysteine, serum vitamin B12 , serum...

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PMID: 24166792
DOI: 10.1002/art.38113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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