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Article

A comparative survey of functional footprints of EGFR pathway mutations in human cancers.

Oncogene - 23 Oct 2014

Lane A, Segura-Cabrera A, Komurov K

Abstract excerpt

Genes functioning in epidermal growth factor receptor (EGFR) signaling pathways are among the most frequently activated oncogenes in human cancers. We have conducted a comparative analysis of functional footprints (that is, effect on signaling and transcriptional landscapes in cells) associated with oncogenic and tumor suppressor mutations in EGFR pathway genes in human cancers. We have found that mutations in...

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Source

Identifiers

PMID: 24166508
DOI: 10.1038/onc.2013.452

Genes

EGFR
ERBB2
AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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