Article
Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity.
The Journal of cell biology - 28 Oct 2013
Araki Yasuhiro, Ku Wei-Chi, Akioka Manami, May Alexander I, Hayashi Yu, Arisaka Fumio, Ishihama Yasushi, Ohsumi Yoshinori
Abstract excerpt
Autophagy is a conserved eukaryotic process of protein and organelle self-degradation within the vacuole/lysosome. Autophagy is characterized by the formation of an autophagosome, for which Vps34-dervied phosphatidylinositol 3-phosphate (PI3P) is essential. In yeast, Vps34 forms two distinct protein complexes: complex I, which functions in autophagy, and complex II, which is involved in protein sorting to the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
