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Article

The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates.

Autophagy - 1 May 2008

Lindmo Karine, Brech Andreas, Finley Kim D, Gaumer Sébastien, Contamine Didier, Rusten Tor Erik, Stenmark Harald

Abstract excerpt

Autophagy is involved in cellular clearance of aggregate-prone proteins, thereby having a cytoprotective function. Studies in yeast have shown that the PI 3-kinase Vps34 and its regulatory protein kinase Vps15 are important for autophagy, but the possible involvement of these proteins in autophag...

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Identifiers

PMID: 18326940
DOI: 10.4161/auto.5829

Genes

SQSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18326940-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates.PMID 18326940Read ↗

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