Article
The origins of genetic variation between individual human oocytes and embryos: implications for infertility.
Human fertility (Cambridge, England) - 1 Dec 2013
Delhanty Joy D A
Abstract excerpt
Human fertility is low in comparison with that seen in other well-studied mammals. The main reason for this state of affairs seems to be the frequent occurrence and persistence of chromosomal errors in the human conceptus. Evidence obtained over the past two decades shows that the exceptionally high incidence of chromosomal anomalies seen in human preimplantation embryos is the result of errors that may occur at...
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