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Meiotic recombination errors, the origin of sperm aneuploidy and clinical recommendations

1 Jan 2011

Abstract excerpt

Since the early 1990s male infertility has successfully been treated by intracytoplasmic sperm injection (ICSI), nevertheless concerns have been raised regarding the genetic risk of ICSI. Chromosome aneuploidy (the presence of extra or missing chromosomes) is the leading cause of pregnancy loss and mental retardation in humans. While the majority of chromosome aneuploidies are maternal in origin, the paternal...

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Share to Assisted Reproductive Technology and Twin Pregnancy
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PMID: 21204593
DOI: 10.3109/19396368.2010.504879

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