Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SerpinB1 deficiency is not associated with increased susceptibility to pulmonary emphysema in mice.

American journal of physiology. Lung cellular and molecular physiology - 1 Dec 2013

Cremona Tiziana P, Tschanz Stefan A, von Garnier Christophe, Benarafa Charaf

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is characterized by emphysema and chronic bronchitis and is a leading cause of morbidity and mortality worldwide. Tobacco smoke and deficiency in α1-antitrypsin (AAT) are the most prominent environmental and genetic risk factors, respectively. Yet the pathogenesis of COPD is not completely elucidated. Disease progression appears to include a vicious circle driven by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bronchoalveolar Lavage Fluid
Share to Disease Susceptibility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, 129 Strain

Share to Mice, Knockout

Share to Pneumonia

Share to Pulmonary Emphysema

Share to Serpins

Source

Identifiers

PMID: 24163143
DOI: 10.1152/ajplung.00181.2013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SerpinB1 deficiency is not associated with increased susceptibility to pulmonary emphysema in mice.PMID 24163143Read ↗

Deletion of Serpina1a, a murine α1-antitrypsin ortholog, results in embryonic lethality.Semantic proximity Read ↗

Lung cellular senescence is independent of aging in a mouse model of COPD/emphysemaSemantic proximity Read ↗

Vulnerability and Genetic Susceptibility to Cigarette Smoke–Induced Emphysema in MiceSemantic proximity Read ↗

Experimental progressive emphysema in BALB/cJ mice as a model for chronic alveolar destruction in humansSemantic proximity Read ↗

The Development of Emphysema in Cigarette Smoke-exposed Mice Is Strain DependentSemantic proximity Read ↗

The Serpin Superfamily and Their Role in the Regulation and Dysfunction of Serine Protease Activity in COPD and Other Chronic Lung DiseasesSemantic proximity Read ↗

Alpha 1 Anti-Trypsin: One Protein, Many FunctionsSemantic proximity Read ↗

State of the Art. Mechanistic Heterogeneity in Chronic Obstructive Pulmonary Disease: Insights from Transgenic MiceSemantic proximity Read ↗

Aging does not Enhance Experimental Cigarette Smoke-Induced COPD in the MouseSemantic proximity Read ↗

Transgenic and gene-targeted mice as models for chronic obstructive pulmonary disease: Fig. 1—Semantic proximity Read ↗

Critical transition in tissue homeostasis accompanies murine lung senescence.Semantic proximity Read ↗

Murine models of asthmaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.