Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-gene interactions in APOL1-associated nephropathy.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Mar 2014

Divers Jasmin, Palmer Nicholette D, Lu Lingyi, Langefeld Carl D, Rocco Michael V, Hicks Pamela J, Murea Mariana, Ma Lijun, Bowden Donald W, Freedman Barry I

Abstract excerpt

BACKGROUND: Two APOL1 nephropathy variants confer substantial risk for non-diabetic end-stage kidney disease (ESKD) in African Americans (AAs). Since not all genetically high-risk individuals develop ESKD, modifying factors likely contribute. Forty-two potentially interactive single nucleotide po...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantigens
Share to Apolipoprotein L1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins

Share to Bone Morphogenetic Protein 4

Share to Glomerular Filtration Rate

Share to Glomerulonephritis

Share to Kidney Failure, Chronic

Share to Lipoproteins, HDL

Source

Open in PubMed Open full text

Identifiers

PMID: 24157943
DOI: 10.1093/ndt/gft423
PMCID: PMC3938297

Genes

APOL1
NPHS2
SDCCAG8
BMP4
ENOX1
TRIB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24157943-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-gene interactions in APOL1-associated nephropathy.PMID 24157943Read ↗

Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy.Semantic proximity Read ↗

Coding variants in nephrin (NPHS1) and susceptibility to nephropathy in African Americans.Semantic proximity Read ↗

Gene-gene and gene-environment interactions in apolipoprotein L1 gene-associated nephropathy.Semantic proximity Read ↗

Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African AmericansSemantic proximity Read ↗

Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.Semantic proximity Read ↗

Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.Semantic proximity Read ↗

Analysis of coding variants identified from exome sequencing resources for association with diabetic and non-diabetic nephropathy in African Americans.Semantic proximity Read ↗

Apolipoprotein L1 (APOL1) and Nephropathy.Semantic proximity Read ↗

A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.Semantic proximity Read ↗

APOL1 Nephropathy: From Genetics to Clinical Applications.Semantic proximity Read ↗

Multi-ethnic polygenic risk modifies the association between <i>APOL1</i> high risk genotypes and chronic kidney diseaseSemantic proximity Read ↗

Relevance of the ACTN4 gene in African-Americans with non-diabetic end-stage renal disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.