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Article

Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.

Gene expression patterns : GEP - 1 Feb 2007

Chiotaki Rena, Petrou Petros, Giakoumaki Elsa, Pavlakis Evangelos, Sitaru Cassian, Chalepakis Georges

Abstract excerpt

The Fras1/Frem gene family encodes for structurally similar, developmentally regulated extracellular matrix proteins. Mutations in Fras1, Frem1 and Frem2 have been identified in different classes of mouse bleb mutants, while defects in the human orthologs FRAS1 and FREM2 are causative for Fraser syndrome. The hallmark phenotypic feature of bleb mice is embryonic skin blistering due to dermal-epidermal detachment....

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Source

Identifiers

PMID: 17251066
DOI: 10.1016/j.modgep.2006.12.001

Genes

FRAS1
FREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.PMID 17251066Read ↗

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