Article
Gene Expression and Methylation Analysis of ABCA7 in Patients with Alzheimer's Disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2017
Yamazaki Kiyohiro, Yoshino Yuta, Mori Takaaki, Yoshida Taku, Ozaki Yuki, Sao Tomoko, Mori Yoko, Ochi Shinichiro, Iga Jun-Ichi, Ueno Shu-Ichi
Abstract excerpt
BACKGROUND/OBJECTIVE: The aim of this study was to examine the blood gene expression and methylation of ATP-binding cassette sub-family A member 7 gene (ABCA7) as a biological marker of AD. METHODS: AD subjects (n = 50; 11 males, 77.7±6.05 years old) and age- and sex-matched healthy controls (n = 50) were recruited. A single nucleotide polymorphism in ABCA7 (rs3764650), methylation rates of CpG sites in the ABCA7...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
