Article
Contribution of fetal ANXA5 gene promoter polymorphisms to the onset of pre-eclampsia.
Placenta - 1 Dec 2013
Ota S, Miyamura H, Nishizawa H, Inagaki H, Inagaki A, Inuzuka H, Suzuki M, Miyazaki J, Sekiya T, Udagawa Y, Kurahashi H
Abstract excerpt
OBJECTIVE: A common haplotype M2 consisting of minor SNP alleles located in the ANXA5 gene promoter region has been described as a risk factor for various obstetric complications such as recurrent pregnancy loss, pre-eclampsia and pregnancy-related thrombophilic disorder. However, the question of whether it is the maternal or fetal genotype that contributes to the onset of these disorders remains to be resolved....
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