Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in the 5' nontranslated region of bovine viral diarrhea virus result in altered growth characteristics.

Journal of virology - 1 Sept 2000

Becher P, Orlich M, Thiel H J

Abstract excerpt

The 5' nontranslated region (NTR) of pestiviruses functions as an internal ribosome entry site (IRES) that mediates cap-independent translation of the viral polyprotein and probably contains additional cis-acting RNA signals involved in crucial processes of the viral life cycle. Computer modeling suggests that the 5'-terminal 75 nucleotides preceding the IRES element form two stable hairpins, Ia and Ib....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Blotting, Northern
Share to Diarrhea Viruses, Bovine Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Viral

Share to Mutagenesis, Site-Directed

Share to Nucleic Acid Conformation

Share to Viral Plaque Assay

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 10933696
DOI: 10.1128/jvi.74.17.7884-7894.2000
PMCID: PMC112319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in the 5' nontranslated region of bovine viral diarrhea virus result in altered growth characteristics.PMID 10933696Read ↗

Essential and nonessential elements in the 3' nontranslated region of Bovine viral diarrhea virus.Semantic proximity Read ↗

A Stem-Loop Motif Formed by the Immediate 5′ Terminus of the Bovine Viral Diarrhea Virus Genome Modulates Translation as well as Replication of the Viral RNASemantic proximity Read ↗

cis-acting RNA elements required for replication of bovine viral diarrhea virus-hepatitis C virus 5' nontranslated region chimeras.Semantic proximity Read ↗

Authentic and chimeric full-length genomic cDNA clones of bovine viral diarrhea virus that yield infectious transcripts.Semantic proximity Read ↗

Hepatitis C virus and the related bovine viral diarrhea virus considerably differ in the functional organization of the 5' non-translated region: implications for the viral life cycle.Semantic proximity Read ↗

Genetic analysis of the pestivirus nonstructural coding region: defects in the NS5A unit can be complemented in trans.Semantic proximity Read ↗

Sequence and Structural Elements at the 3′ Terminus of Bovine Viral Diarrhea Virus Genomic RNA: Functional Role during RNA ReplicationSemantic proximity Read ↗

Functional Characterization of Bovine Viral Diarrhea Virus Nonstructural Protein 5A by Reverse Genetic Analysis and Live Cell ImagingSemantic proximity Read ↗

Complex signals in the genomic 3′ nontranslated region of bovine viral diarrhea virus coordinate translation and replication of the viral RNASemantic proximity Read ↗

Characterization of an Autonomous Subgenomic Pestivirus RNA RepliconSemantic proximity Read ↗

cis Requirement for N-specific protein sequence in bovine coronavirus defective interfering RNA replicationSemantic proximity Read ↗

RNA Recombination between Persisting Pestivirus and a Vaccine Strain: Generation of Cytopathogenic Virus and Induction of Lethal DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.