Article
Genetic analysis of the pestivirus nonstructural coding region: defects in the NS5A unit can be complemented in trans.
Journal of virology - 1 Sept 2001
Grassmann C W, Isken O, Tautz N, Behrens S E
Abstract excerpt
The functional analysis of molecular determinants which control the replication of pestiviruses was considerably facilitated by the finding that subgenomic forms of the positive-strand RNA genome of BVDV (bovine viral diarrhea virus) are capable of autonomous replication in transfected host cells. The prototype replicon, BVDV DI9c, consists of the genomic 5' and 3' untranslated regions and a truncated open...
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