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Article

Dysmorphic patterns are associated with cytoskeletal alterations in human oocytes

16 Feb 2017

Abstract excerpt

Study question: Are specific morphological anomalies in human mature oocytes, as revealed by transmitted light microscopy, associated with intrinsic damage to the meiotic spindle and actin cytoskeleton? Summary answer: Aggregates of smooth endoplasmic reticulum (SER) and domains of centrally localized granular cytoplasm (GC) reflect intrinsic damage to the oocyte cytoskeleton, namely alterations in spindle size,...

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PMID: 28333241
DOI: 10.1093/humrep/dex041

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