Article
Transcriptional regulation in pluripotent stem cells by methyl CpG-binding protein 2 (MeCP2).
Human molecular genetics - 15 Feb 2014
Tanaka Yoshiaki, Kim Kun-Yong, Zhong Mei, Pan Xinghua, Weissman Sherman Morton, Park In-Hyun
Abstract excerpt
Rett syndrome (RTT) is one of the most prevalent female mental disorders. De novo mutations in methyl CpG-binding protein 2 (MeCP2) are a major cause of RTT. MeCP2 regulates gene expression as a transcription regulator as well as through long-range chromatin interaction. Because MeCP2 is present...
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