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Article

Amino acids as biomarkers in the SOD1(G93A) mouse model of ALS.

Biochimica et biophysica acta - 1 Jan 2014

Bame Monica, Grier Robert E, Needleman Richard, Brusilow William S A

Abstract excerpt

The development of therapies for Amyotrophic Lateral Sclerosis (ALS) has been hindered by the lack of biomarkers for both identifying early disease and for monitoring the effectiveness of drugs. The identification of ALS biomarkers in presymptomatic individuals might also provide clues to the earliest biochemical correlates of the disease. Previous attempts to use plasma metabolites as biomarkers have led to...

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Amino Acids
Amyotrophic Lateral Sclerosis
Glutamate-Ammonia Ligase
Longevity
Metabolome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Superoxide Dismutase

Superoxide Dismutase-1

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Identifiers

PMID: 24129262
DOI: 10.1016/j.bbadis.2013.10.004

Genes

SOD1

Variants

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