Article
The mammalian low-density lipoprotein receptor family.
Annual review of nutrition - 1 Jan 1999
Hussain M M, Strickland D K, Bakillah A
Abstract excerpt
The low-density lipoprotein (LDL) receptor (LDL-R) family consists of cell-surface receptors that recognize extracellular ligands and internalize them for degradation by lysosomes. The LDL-R is the prototype of this family, which also contains very-low-density lipoprotein receptors (VLDL-R), apolipoprotein E receptor 2, LRP, and megalin. The family members contain four major structural modules: the cysteine-rich...
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