Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterisation of Mycobacterium tuberculosis isolates lacking IS6110 in Viet Nam.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Nov 2013

Huyen M N T, Tiemersma E W, Kremer K, de Haas P, Lan N T N, Buu T N, Sola C, Cobelens F G J, van Soolingen D

Abstract excerpt

SETTING: The molecular diagnosis of tuberculosis (TB) in Viet Nam is often based on the detection of insertion sequence (IS) 6110 in Mycobacterium tuberculosis. However, 8-11% of M. tuberculosis strains in South-East Asia do not contain this target and this undermines the validity of these molecular tests. OBJECTIVE: We quantified the frequency of M. tuberculosis strains lacking IS6110 in rural Viet Nam and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amplified Fragment Length Polymorphism Analysis
Share to Antitubercular Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to False Negative Reactions

Share to Molecular Diagnostic Techniques

Share to Rural Health

Share to Sputum

Share to Tuberculosis, Pulmonary

Share to Vietnam

Source

Identifiers

PMID: 24125454
DOI: 10.5588/ijtld.13.0149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterisation of Mycobacterium tuberculosis isolates lacking IS6110 in Viet Nam.PMID 24125454Read ↗

Variable-number tandem repeats typing of Mycobacterium tuberculosis isolates with low copy numbers of IS6110 in Thailand.Semantic proximity Read ↗

Evolutionary Relationships among Strains of Mycobacterium tuberculosis with Few Copies of IS 6110Semantic proximity Read ↗

Genotyping Mycobacterium tuberculosis isolates with few copies of IS6110: Value of additional genetic markers.Semantic proximity Read ↗

Analysis of sequence diversity among IS6110 sequence of Mycobacterium tuberculosis: possible implications for PCR based detectionSemantic proximity Read ↗

Rapid Quantification of IS6110 Copy Number in<i>M. tuberculosis</i>Using Dual-Target qPCR AssaySemantic proximity Read ↗

IS6110 in oriC affects the morphology and growth of Mycobacterium tuberculosis and attenuates virulence in mice.Semantic proximity Read ↗

IS6110 restriction fragment length polymorphism typing of clinical isolates of Mycobacterium tuberculosis from patients with pulmonary tuberculosis in Madras, South IndiaSemantic proximity Read ↗

Optimized Lysis-Extraction Method Combined With IS6110-Amplification for Detection of Mycobacterium tuberculosis in Paucibacillary Sputum SpecimensSemantic proximity Read ↗

Molecular differentiation of Mycobacterium tuberculosis strains without IS6110 insertions.Semantic proximity Read ↗

Mapping IS6110 in high-copy number Mycobacterium tuberculosis strains shows specific insertion points in the Beijing genotype.Semantic proximity Read ↗

Disruption of coding regions by IS6110 insertion in Mycobacterium tuberculosis.Semantic proximity Read ↗

Restriction fragment length polymorphism analysis using IS6110 as an epidemiological marker in tuberculosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.