Article
Disruption of coding regions by IS6110 insertion in Mycobacterium tuberculosis.
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Jan 1999
Sampson S L, Warren R M, Richardson M, van der Spuy G D, van Helden P D
Abstract excerpt
SETTING: The insertion sequence IS6110 is widely used as a DNA fingerprinting probe for the classification of Mycobacterium tuberculosis strains. This study has focused on the characterization of regions disrupted by insertion of the IS6110 element. OBJECTIVE: To characterize IS6110 insertion loci in clinical isolates of M. tuberculosis, in terms of their genomic location and genetic identity, to ascertain...
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