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Genotyping Mycobacterium tuberculosis isolates with few copies of IS6110: Value of additional genetic markers.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2020

Arora Jyoti, Suresh Naga, Porwal Chhavi, Pandey Pooja, Pande Jitendra Nath, Singh Urvashi Balbir

Abstract excerpt

PURPOSE: IS6110 restriction fragment length polymorphism (RFLP) analysis is widely used for molecular epidemiological studies of tuberculosis. Role of spoligotyping and Fluorescent Amplified Fragment Length Polymorphism (FAFLP) was studied in low-copy number IS6110 strains of Mycobacterium tuberculosis complex (Mtbc). METHODS: The study isolates included 70 strains of Mtbc collected from different regions of...

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PMID: 32035976
DOI: 10.1016/j.meegid.2020.104230

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